2013-2017

1. Zhu S*, Ding S*, Wang P, Wang G, Lei X, Palm N, Pan W, Zheng Y, Feng N, Lu J, Shan L, Abraham C, Fikrig E, Greenberg H#,Flavell R#. Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells. 2017. Nature. doi:10.1038/nature22967.   

2. Wang P*, Zhu S*, Yang L, Cui S, Pan W, Jackson CelR, Zheng Y, Rongvaux A, Sun Q, Yang G, Gao S, Lin R, You F, Flavell R#, Fikrig E#. Nlrp6 regulatesintestinal antiviral innateimmunity. Science.10.1126/science. aab 3145. (Comment in Science Signaling (2015) DOI: 10.1126/scisignal.aad8628, *co-first author, #co-corresponding author)

3. Li, H.*, J. Tong*, S. Zhu*, P. Batista, J.Zhao, W. Bailis, Y. Yang, G. Wang, Y. Chen, Y. Kluger, Howard Y. Chang, Zhinan Yin#, Richard A. Flavell#. m6A mRNA methylation controls T cell homeostasis by targeting the IL-7STAT5SOCS pathways. Nature. doi:10.1038/nature23450. (*co-first author)

4. Pan W*, Zhu S*, Dai D, Liu Z, Li D, Li B, Gagliani N, Zheng Y,.. Qian Y, Chen Y, Fang J, Herbst R, Richman L, Jallal B, Harley J, Flavell R, Yao Y# and Shen N#. MiR-125a targets effector programs to stabilize Treg mediated immune homeostasis and controls autoimmunity. Nature Communication. DOI: 10.1038/ncomms8096. (*co-first author)

5.Pan W, Zhu S, K Qu, K Meeth, J Cheng, K He, H Ma, Y Liao, X Wen, C Roden, Z Tobiasova, Z Wei, J Zhao, J Liu, J Zheng, B Guo, M Bosenberg, R Flavell, J Lu#. Tet2 sustains the immunosuppressive function of myeloid cells and promotes melanoma growth. Immunity. 2017, doi: 10.1016/j.immuni.2017.07.020. 

6. Zhu S, Li HB, Flavell RA#. Resemble and Inhibit when RLR meets TGF-b. Molecular Cell. Dec 18;56(6): 719-20. doi:10.1016/j.molcel.2014.12.010.

7. Zhu S, Jackson R, Flavell RA#. The lock-washer a reconciliation of the RIG-I activation models. Cell Research.10.1038/cr.2014.5.

8. Shu Zhu, Geng Wang, Xuqiu Lei, Richard A. Flavell#. Mex3B, a coreceptor to present dsRNA to TLR3. Cell Research. 26(4):391-2. doi: 10.1038/cr.2016.29.

9. Hu B, Jin C, Li HB, Tong J, Ouyang X, Cetinbas NM, Zhu S, Strowig T, Lam FC, Zhao C, Henao-Mejia J, Yilmaz O, Fitzgerald KA, Eisenbarth SC, Elinav E, Flavell RA#. The DNA Sensing Aim2 Inflammasome Controls Radiation Induced Cell death and Tissue Injury. Science. 2016 Nov 11;354(6313):765-768.

10. Song X, Dai D, He X, Zhu S, Yao Y, Gao H, Wang J, Qu F, Qiu J, Wang H, Li X, Shen N, Qian Y#. Growth Factor FGF2 Cooperates with Interleukin-17 to Repair Intestinal Epithelial Damage.Immunity. doi:10.1016/j.immuni.2015.06.024.

11. Song X, Gao H, Lin Y, Yao Y, Zhu S, Wang J, Liu Y, Yao X, Meng G, Shen N, Shi Y, Iwakura Y, Qian Y#.  Alterations in the Microbiota Drive Interleukin-17C Production from Intestinal Epithelial Cells to Promote Tumorigenesis. Immunity. 40 (1), 140-152.

12. Cheng J, Roden CA, Pan W, Zhu S, Baccei A, Pan X, Jiang T, Kluger Y, Weissman SM, Guo S, Flavell RA, Ding Y, Lu J#.A Molecular Chipper Technology for CRISPR sgRNA Library Generation and Functional Mapping of Noncoding Regions. Nature Communication. 7:11178. doi: 10.1038/ncomms11178.  

13. H Yu, N Gagliani, H Ishigame, S Huber, S Zhu, E Esplugues, K Herold, L Wen, R Flavell#. Intestinal type 1 regulatory T cells migrate to periphery to suppress diabetogenic T cells and prevent diabetes development. Proceedings of the National Academy of Sciences, doi: 8.1073/pnas.1705599114.

14. Cao J, Zhu S, Zhou W, Li J, Liu C, Xuan H, Yan J, Zheng L, Zhou L, Yu J, Chen G, Huang Y, Yu Z, Feng L#.  PLZF Mediates the PTENAKTFOXO3a Signaling in Suppression of Prostate Tumorigenesis. PLoS One. 8 (12), e77922

15. Yu H, Borsotti C, Schickel JN, Zhu S, Strowig T, Eynon EE, Frleta D, Gurer C, Murphy AJ, Yancopoulos GD, Meffre E, Manz MG, Flavell RA#. A novel humanized mouse model with significant improvement of. Blood.   doi: 10.1182/blood-2016-04-709584.

16. W Pan, S Zhu, D Dai, J Harley, N Shen#. T Cell Transfer Model of Colitis. Bio-protocol.10.21769/BioProtoc.1862

17. Marcel R. de Zoete*, Noah W. Palm*, Shu Zhu*, Richard A. Flavell#. 2014.  Inflammasomes. Cold Spring Haber Perspectives in Biology. Oct 16;6(12):a016287. doi: 10.1101/cshperspect.a016287 (*co-first author)

18. W Pan, S Zhu, D Dai, J Harley, N Shen#. Mir-125a Is Critical Regulator for Controlling Autoimmunity in Multiple Autoimmune Diseases through Stabilizing Treg Mediated Immune Homeostasis. Arthritis &Rheumatology. 66():S1245, OCT 2014.

19. Zhu S#, Pan W, Qian Y#. MicroRNA in immunity and autoimmunity. J Mol Med. Sep;91(9):1039-50. doi: 10.1007/s00109-013-1043-z. (#co-corresponding author; Invited review).